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Index > Protein center > CRAT(Gene name) > Human
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  • CRAT (Gene name),
  • Carnitine O-acetyltransferase (Protein name ),  CACP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CRAT(CAT1);
    Protein name:
    Carnitine O-acetyltransferase(Carnitine acetylase);
    Alternative:
    Carnitine acetyltransferase(CAT;CrAT);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.
    Subcellular Location:
    Isoform 2 Peroxisome
    Protein Attributes:
    Sequence length:
    626
    Sequence:
    50:
    MLAFAARTVV | KPLGFLKPFS | LMKASSRFKA | HQDALPRLPV | PPLQQSLDHY | 
    100:
    LKALQPIVSE | EEWAHTKQLV | DEFQASGGVG | ERLQKGLERR | ARKTENWLSE | 
    150:
    WWLKTAYLQY | RQPVVIYSSP | GVMLPKQDFV | DLQGQLRFAA | KLIEGVLDFK | 
    200:
    VMIDNETLPV | EYLGGKPLCM | NQYYQILSSC | RVPGPKQDTV | SNFSKTKKPP | 
    250:
    THITVVHNYQ | FFELDVYHSD | GTPLTADQIF | VQLEKIWNSS | LQTNKEPVGI | 
    300:
    LTSNHRNSWA | KAYNTLIKDK | VNRDSVRSIQ | KSIFTVCLDA | TMPRVSEDVY | 
    350:
    RSHVAGQMLH | GGGSRLNSGN | RWFDKTLQFI | VAEDGSCGLV | YEHAAAEGPP | 
    400:
    IVTLLDYVIE | YTKKPELVRS | PLVPLPMPKK | LRFNITPEIK | SDIEKAKQNL | 
    450:
    SIMIQDLDIT | VMVFHHFGKD | FPKSEKLSPD | AFIQMALQLA | YYRIYGQACA | 
    500:
    TYESASLRMF | HLGRTDTIRS | ASMDSLTFVK | AMDDSSVTEH | QKVELLRKAV | 
    550:
    QAHRGYTDRA | IRGEAFDRHL | LGLKLQAIED | LVSMPDIFMD | TSYAIAMHFH | 
    600:
    LSTSQVPAKT | DCVMFFGPVV | PDGYGVCYNP | MEAHINFSLS | AYNSCAETNA | 
    626:
    ARLAHYLEKA | LLDMRALLQS | HPRAKL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    UniGene:
    SMR:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Carnitine acetylase
    Cat.:
    E9675h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Carnitine acetylase
    Cat.:
    E9675r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Carnitine acetylase
    Cat.:
    E9675m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Carnitine acetylase
    Cat.:
    U9675m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Carnitine acetylase
    Cat.:
    U9675h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Carnitine acetylase
    Cat.:
    U9675r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Carnitine acetylase
    Cat.:
    P9675Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Carnitine acetylase
    Cat.:
    P9675Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Carnitine acetylase
    Cat.:
    P9675Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Carnitine acetylase
    Monoclonal Antibody for Human Carnitine acetylase
    Monoclonal Antibody for Human Carnitine acetylase
    Protein for Human Carnitine acetylase
    Protein for Human Carnitine acetylase
    Protein for Human Carnitine acetylase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT MET-372
    2. 2.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT MET-372
      tissue: Placenta.
    4. 4.
      "Divergent sequences in the 5' region of cDNA suggest alternative splicing as a mechanism for the generation of carnitine acetyltransferases with different subcellular localizations."
      Corti O. , DiDonato S. , Finocchiaro G.
      Biochem. J.303:37-41(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-52 (ISOFORMS 1 AND 2);ALTERNATIVE SPLICING
    5. 5.
      "Molecular cloning of cDNAs encoding human carnitine acetyltransferase and mapping of the corresponding gene to chromosome 9q34.1."
      Corti O. , Finocchiaro G. , Rossi E. , Zuffardi O. , Didonato S.
      Genomics23:94-99(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3-626 (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;VARIANT MET-372
    6. 6.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-261 AND LYS-268;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer."
      Wu D. , Govindasamy L. , Lian W. , Gu Y. , Kukar T. , Agbandje-McKenna M. , McKenna R.
      J. Biol. Chem.278:13159-13165(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 35-626;SUBUNIT
    8. 8.
      "Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase."
      Govindasamy L. , Kukar T. , Lian W. , Pedersen B. , Gu Y. , Agbandje-McKenna M. , Jin S. , McKenna R. , Wu D.
      J. Struct. Biol.146:416-424(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 35-626 IN COMPLEX WITH CARNITINE;MUTAGENESIS OF TYR-452; THR-465; ARG-518 AND PHE-566
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